Weil-Supported Member Publications

2023

• AI-Based Decision Support System for Traumatic Brain Injury: A Survey
  DOI: 10.3390/diagnostics13091640

• Association between bystander physical limitations, delays in chest compression during telecommunicator-assisted cardiopulmonary resuscitation, and outcome after out-of-hospital cardiac arrest
  DOI: 10.1016/j.resuscitation.2023.109816

• A Tissue Chip with Integrated Digital Immunesensors: In Situ Brain Endothelial Barrier Cytokine Secretion Monitoring 
  DOI: 10.1016/j.bios.2022.115030

• Bioinspired Plasmo-virus for Point-of-Care for SARS-CoV-2 Detection 
  DOI: 10.1021/acs.nanolett.2c03700

• Clofazimine-Mediated, Age-Related Changes in Skeletal Muscle Mitochondrial Metabolites
  DOI: 10.3390/metabo13050671

• Development and Retention of Early-Career Clinician-Scientists Through a Novel Peer Mentorship Program: Multidisciplinary Intensive Care Research Workgroup 
  DOI: 0.34197/ats-scholar.2022-0039IN

• Extracorporeal Cardiopulmonary Resuscitation for Cardiac Arrest: An Updated Systematic Review 
  DOI: 10.1016/j.resuscitation.2022.12.003

• Factors Impacting Treatment of Out-of-Hospital Cardiac Arrest: A Qualitative Study of Emergency Responders
  DOI: 10.1161/JAHA.122.027756

• Haemodynamic impact of aortic balloon occlusion combined with percutaneous left ventricular assist device during cardiopulmonary resuscitation in a swine model of cardiac arrest
  DOI: 10.1016/j.resuscitation.2023.109885

• In Patients With Sepsis, Initial Lactate Clearance Is Confounded Highly by Comorbidities and Poorly Predicts Subsequent Lactate Trajectory
  DOI: 10.1016/j.chest.2023.04.023

• Is Anion Gap Helpful for Assessing Cardiovascular Risk in Cardiac Intensive Care Unit? 
  DOI: 10.1253/circj.CJ-22-0658

• Is it Time to Discuss Centralization of Extracorporeal Membrane Oxygenation Centers? 
  DOI: 10.1016/j.ijcard.2022.11.009

• Precision-based approaches to delirium in critical illness: A narrative review
  DOI: 10.1002/phar.2807

• Reply to: Anti-anaerobic antibiotics: indication is key
  DOI: 10.1183/13993003.00492-2023

• Subphenotypes Assigned to Pediatric Acute Respiratory Failure Patients Show Differing Outcomes
  DOI: 10.1164/rccm.202301-0070LE

• The Gut Microbiome in ARDS: From the "Whether" and "What" to the "How" 
  DOI: 10.1183/13993003.02233-2022

• The Gut Microbiome Modulates Body Temperature Both in Sepsis and Health 
  DOI: 10.1164/rccm.202201-0161OC

• Therapeutic Effect of Argatroban During Cardiopulmonary Resuscitation and Streptokinase During Extracorporeal Cardiopulmonary Resuscitation in a Porcine Model of Prolonged Cardiac Arrest
  DOI: 10.1097/CCE.0000000000000902

• The Two-Bag Method for Management of Adult Diabetic Ketoacidosis-Experience With 634 Patients
  DOI: 10.1177/08850666231175387

• Ultrathin Silica Integration for Enhancing Reliability of Microfluidic Photoionization Detectors
  DOI: 10.1080/10903127.2023.2183533

2022

• Chanderraj R, Brown CA, Hinkle K, Falkowski N, Woods RJ, Dickson RP. The bacterial density of clinical rectal swabs is highly variable, correlates with sequencing contamination, and predicts patient risk of extraintestinal infection. Microbiome. 2022 Jan 6;10(1):2. doi: 10.1186/s40168-021-01190-y. PMID: 34991717; PMCID: PMC8734160.

• Harvey CE, Haas NL, Chen CM, Cranford JA, Hamera JA, Havey RA, Tsuchida RE, Bassin BS. Initiation of a Lung Protective Ventilation Strategy in the Emergency Department: Does an Emergency Department-Based ICU Make a Difference? Crit Care Explor. 2022 Feb 8;4(2):e0632. doi: 10.1097/CCE.0000000000000632. PMID: 35156050; PMCID: PMC8826963.

• Farzaneh N, Stein EB, Soroushmehr R, Gryak J, Najarian K. A deep learning framework for automated detection and quantitative assessment of liver trauma. BMC Med Imaging. 2022 Mar 8;22(1):39. doi: 10.1186/s12880-022-00759-9. PMID: 35260105; PMCID: PMC8905785.

• Bongers KS, McDonald RA, Winner KM, Falkowski NR, Brown CA, Baker JM, Hinkle KJ, Fergle DJ, Dickson RP. Antibiotics cause metabolic changes in mice primarily through microbiome modulation rather than behavioral changes. PLoS One. 2022 Mar 17;17(3):e0265023. doi: 10.1371/journal.pone.0265023. PMID: 35298489; PMCID: PMC8929607.

• Dowker SR, Smith G, O'Leary M, Missel AL, Trumpower B, Hunt N, Herbert L, Sams W, Kamdar N, Coulter-Thompson EI, Shields T, Swor R, Domeier R, Abir M, Friedman CP, Neumar RW, Nallamothu BK; Emergent Health Partners Collaborators. Assessment of telecommunicator cardiopulmonary resuscitation performance during out-of-hospital cardiac arrest using a standardized tool for audio review. Resuscitation. 2022 Apr 26:S0300-9572(22)00133-2. doi: 10.1016/j.resuscitation.2022.04.015. Epub ahead of print. PMID: 35483496.

• Schmitzberger FF, Hall AE, Hughes ME, Belle A, Benson B, Ward KR, Bassin BS. Detection of Hemodynamic Status Using an Analytic Based on an Electrocardiogram Lead Waveform. Crit Care Explor. 2022 May 17;4(5):e0693. doi: 10.1097/CCE.0000000000000693. PMID: 35620767; PMCID: PMC9116956.

• Daniels RC, Tiba MH, Cummings BC, Yap YR, Ansari S, McCracken BM, Sun Y, Jennaro TS, Ward KR, Stringer KA. Redox Potential Correlates with Changes in Metabolite Concentrations Attributable to Pathways Active in Oxidative Stress Response in Swine Traumatic Shock. Shock. 2022 Jun 1;57(6):282-290. doi: 10.1097/SHK.0000000000001944. Epub 2022 May 31. PMID: 35670453.

• Lin S, Ramadeen A, Sundermann ML, Dorian P, Fink S, Halperin HR, Kiss A, Koller AC, Kudenchuk PJ, McCracken BM, Mohindra R, Morrison LJ, Neumar RW, Niemann JT, Salcido DD, Tiba MH, Youngquist ST, Zviman MM, Menegazzi JJ. Establishing a multicenter, preclinical consortium in resuscitation: A pilot experimental trial evaluating epinephrine in cardiac arrest. Resuscitation. 2022 Jun;175:57-63. doi: 10.1016/j.resuscitation.2022.04.016. Epub 2022 Apr 23. PMID: 35472628.

• Gottula, A. , Neumar, R. & Hsu, C. (2022). Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest - who, when, and where?. Current Opinion in Critical Care, 28 (3), 276-283. doi: 10.1097/MCC.0000000000000944.

• Daniels RC, Tiba MH, Cummings BC, Yap YR, Ansari S, McCracken BM, Sun Y, Jennaro TS, Ward KR, Stringer KA. Redox Potential Correlates with Changes in Metabolite Concentrations Attributable to Pathways Active in Oxidative Stress Response in Swine Traumatic Shock. Shock. 2022 Jun 1;57(6):282-290. doi: 10.1097/SHK.0000000000001944. Epub 2022 May 31. PMID: 35670453

• Krishnamoorthy M, Ranjan P, Erb-Downward JR, Dickson RP, Wiens J. AMAISE: a machine learning approach to index-free sequence enrichment. Commun Biol. 2022 Jun 9;5(1):568. doi: 10.1038/s42003-022-03498-3. PMID: 35681015; PMCID: PMC9184628.

• Ranjan P, Brown CA, Erb-Downward JR, Dickson RP. SNIKT: sequence-independent adapter identification and removal in long-read shotgun sequencing data. Bioinformatics. 2022 Jun 13:btac389. doi: 10.1093/bioinformatics/btac389. Epub ahead of print. PMID: 35695743.

• Yazer MH, Beckett A, Corley J, Devine DV, Studer NM, Taylor AL, Ward KR, Cap AP. Tips, tricks, and thoughts on the future of prehospital blood transfusions. Transfusion. 2022 Jun 24. doi: 10.1111/trf.16955. Epub ahead of print. PMID: 35748682.

• Schmitzberger FF, Haas NL, Coute RA, Bartos J, Hackmann A, Haft JW, Hsu CH, Hutin A, Lamhaut L, Marinaro J, Nagao K, Nakashima T, Neumar R, Pellegrino V, Shinar Z, Whitmore SP, Yannopoulos D, Peterson WJ. ECPR2: Expert Consensus on PeRcutaneous cannulation for Extracorporeal CardioPulmonary Resuscitation. Resuscitation. 2022 Jul 8:S0300-9572(22)00593-7. doi: 10.1016/j.resuscitation.2022.07.003. Epub ahead of print. PMID: 35817270.

• Nakashima T, Ogata S, Noguchi T, Nishimura K, Hsu CH, Sefa N, Haas NL, Bĕlohlávek J, Pellegrino V, Tonna JE, Haft J, Neumar RW. Association of intentional cooling, achieved temperature and hypothermia duration with in-hospital mortality in patients treated with extracorporeal cardiopulmonary resuscitation: An analysis of the ELSO registry. Resuscitation. 2022 Aug;177:43-51. doi: 10.1016/j.resuscitation.2022.06.022. Epub 2022 Jul 3. PMID: 35788020.

• Korley F, Jain S, Sun X, et al. Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic braininjury in patients from the US TRACK-TBI cohort: an observational cohort study. Lancet Neurology 2022. doi: 10.1016/S1474-4422(22)00256-32

• Pantaleón García J, Dickson RP, Evans SE. Minimizing caging effects in murine lung microbiome studies. Am J Physiol Lung Cell Mol Physiol. 2022 Aug 1;323(2):L219-L220. doi: 10.1152/ajplung.00144.2022. PMID: 35944140; PMCID: PMC9377779.

• Sjoding MW, Ansari S, Valley TS. Origins of Racial and Ethnic Bias in Pulmonary Technologies. Annu Rev Med. 2022 Jul 28. doi: 10.1146/annurev-med-043021-024004. Epub ahead of print. PMID: 35901314.

• Tyagi S, Brown CA, Dickson RP, Sjoding MW. Outcomes and Predictors of Severe Hyperoxemia in Patients Receiving Mechanical Ventilation: A Single-Center Cohort Study. Ann Am Thorac Soc. 2022 Aug;19(8):1338-1345. doi: 10.1513/AnnalsATS.202107-804OC. PMID: 35157559; PMCID: PMC9353951.

• Maile MD, Mathis MR, Jewell ES, Mentz GB, Engoren MC. Identification of intraoperative management strategies that have a differential effect on patients with reduced left ventricular ejection fraction: a retrospective cohort study. BMC Anesthesiol. 2022 Sep 10;22(1):288. doi: 10.1186/s12871-022-01817-z. PMID: 36088308.

Weil publications relating to our research and products in the area of Sepsis and Multi-organ Failure.

Analytic for Predicting ARDS

• Learning Using Partially Available Privileged Information and Label Uncertainty: Application in Detection of Acute Respiratory Distress Syndrome, July 10, 2020, IEEE Journal of Biomedical and Health Informatics

• Robust segmentation of lung in chest x-ray: applications in analysis of acute respiratory distress syndrome, October 15, 2020, BMC of Medical Imaging

• Signal quality measure for pulsatile physiological signals using morphological features: Applications in reliability measure for pulse oximetry, 2019, Informatics in Medicine Unlocked

ARDS Model

• A novel swine model of the acute respiratory distress syndrome using clinically relevant injury exposures

Bacterial Translocation in Sepsis: A Multifaceted Molecular Approach

• Bacterial Dissemination to the Brain in Sepsis, March 15, 2018, American Journal of Respiratory and Critical Care Medicine Volume 197 Number 6

• Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome, July 18, 2016, Nature Microbiology

• Bacterial Dissemination to the Brain in a Murine Model of Treated Sepsis, 2016, American Journal of Respiratory and Critical Care Medicine

Blood Biomarker Guided Diagnosis System for Inflammation

• An Integrated Plasmo-Photoelectronic Nanostructure Biosensor Detects an Infection Biomarker Accompanying Cell Death in Neutrophils, Dec 3, 2019, Small Journal

• Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays, March 20, 2015, ACS Publications

• AC Electroosmosis-Enhanced Nanoplasmofluidic Detection of Ultralow-Concentration Cytokine, March 15, 2017, ACS Publications

• Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure, June 22, 2016, ACS Pub

• Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, MARCH 25, 2021, Blood

• Biotunable Nanoplasmonic Filter on Few-Layer MoS2 for Rapid and Highly Sensitive Cytokine Optoelectronic Immunosensing, May 10, 2017, ACS Pub

Breath Analysis Device for Lung Disease Detection

• Rapid breath analysis for acute respiratory distress syndrome diagnostics using a portable two-dimensional gas chromatography device, August, 2019, Analytic & Bioanalytic Chemistry

• Real Time Breath Analysis Using Portable Gas Chromatography for Adult Asthma Phenotypes, Metabolites 11, 265 (2021) Detect ARDS

• Deep learning to detect acute respiratory distress syndrome on chest radiographs: a retrospective study with external validation, April 20, 2021, Lancet

Rapid Pathogen Identification in Pneumonia Using Real-time Metagenomics and Ultra-sensitive PCR

• Rapid Pathogen Identification in Bacterial Pneumonia Using Real-Time Metagenomics, May 5, 2017, American Journal of Respiratory and Critical Care Medicine

Redox Point-of-Care Platform

• Electrochemical properties of nanostructured porous gold electrodes in biofouling solutions, 2013 Dec 3;85(23):11610-8. doi: 10.1021/ac403013r. Epub 2013 Nov 18, Analytical Chemistry

• Whole Blood Redox Potential Correlates With Progressive Accumulation of Oxygen Debt and Acts as A Marker of Resuscitation in A Swine Hemorrhagic Shock Model, March 2018, Shock

Sepsis Model

• A comprehensive assessment of multi-system responses to a renal inoculation of uropathogenic E. coli in swine

The Role of the Lung Microbiome in Oxygen-Induced Lung Injury

• The role of the bacterial microbiome in lung disease, Published online: 09 Jan 2014, Expert Review of Respiratory Medicine

• The Microbiome and the Respiratory Tract, February 2016, Annual Review of Physiology

• Understanding the role of the microbiome in chronic obstructive pulmonary disease: principles, challenges, and future directions, January 1, 2017, Translational Research

• The bacterial microbiota in inflammatory lung diseases, August 2015, Clinical Immunology

TOBI

• Trans-ocular brain impedance index for assessment of cerebral autoregulation in a porcine model of cerebral hemodynamic perturbation, July 14, 2020, Journal of Clinical Monitoring and Computing

• Novel Noninvasive Method of Cerebrovascular Blood Volume Assessment Using Brain Bioimpedance, November 15, 2017, Journal of Neurotrauma

• Trans-Ocular Brain Impedance Indices Predict Pressure Reactivity Index Changes in a Porcine Model of Hypotension and Cerebral Autoregulation Perturbation, Neurocrit Care, July 9, 2021

Weil publications relating to our research and products in the area of Neurologic Emergencies.

Automated Brain Image Analysis of Subdural Hematoma

• Novel Algorithm for Automated Optic Nerve Sheath Diameter Measurement Using a Clustering Approach Military Medicine, Volume 186, Issue Supplement_1, January-February 2021, Pages 496–501,

• Automated Segmentation and Severity Analysis of Subdural Hematoma for Patients with Traumatic Brain Injuries, Diagnostics 2020, 10(10), 773

• Automated hematoma segmentation and outcome prediction for patients with traumatic brain injury, Artificial Intelligence in Medicine, Vol 107, July 2020

• Midline Shift vs. Mid-Surface Shift: Correlation with Outcome of Traumatic Brain Injuries, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

• Automated Optic Nerve Sheath Diameter Measurement Using Super-pixel Analysis, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, pp 2793-2796, doi: 10.1109/EMBC.2019.8856449

• Brain Hematoma Segmentation Using Active Learning and an Active Contour Model. In: Rojas I., Valenzuela O., Rojas F., Ortuño F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2019. Lecture Notes in Computer Science, vol 11466. Springer, Cham.

• Hematoma Segmentation Using Dilated Convolutional Neural Network, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018, pp. 5902-5905

• Automatic Midline Shift Detection in Traumatic Brain Injury, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018

Diagnostic Tool for Coagulation Abnormalities in TBI

• A droplet-based microfluidic viscometer for the measurement of blood coagulation, Jan 2020, Biomicrofluidics

Point-of-Care Microfluidic Platform for Detecting Traumatic Brain Injury

• Variable-height channels for microparticle characterization and display, 21 July 2020, Issue 14, Lab on a Chip,

TOBI

• Trans-Ocular Brain Impedance Indices Predict Pressure Reactivity Index Changes in a Porcine Model of Hypotension and Cerebral Autoregulation Perturbation, February 2022, Neurocritical Care

• Trans-ocular brain impedance index for assessment of cerebral autoregulation in a porcine model of cerebral hemodynamic perturbation, July 14, 2020, Journal of Clinical Monitoring and Computing

• Novel Noninvasive Method of Cerebrovascular Blood Volume Assessment Using Brain Bioimpedance, November 15, 2017, Journal of Neurotrauma

Weil publications relating to our research and products in the area of Critical Heart Conditions.

AHI

• A Signal Processing Approach for Detection of Hemodynamic Instability before Decompensation, February 12, 2016, PLOS

Cardiac Arrest

• Intrastate Variation in Treatment and Outcomes of Out-of-Hospital Cardiac Arrest

• Aerosol generation during chest compression and defibrillation in a swine cardiac arrest model

• Dose optimization of early high-dose valproic acid for neuroprotection in a swine cardiac arrest model

DRIVE

• Dynamic Limb Bioimpedance and Inferior Vena Cava Ultrasound in Patients Undergoing Hemodialysis, August 2016, ASAIO

• Continuous Inferior Vena Cava Diameter Tracking through an Iterative Kanade–Lucas–Tomasi-Based Algorithm,Sept 10, 2018, Ultrasound in Medicine & Biology

Electrocardiomatrix (ECM)

• Accurate detection of atrial fibrillation and atrial flutter using the electrocardiomatrix technique, August 2018, J Electrocardiology

• Electrocardiomatrix facilitates qualitative identification of diminished heart rate variability in critically ill patients shortly before cardiac arrest, August 2018, J Electrocardiology

• Electrocardiomatrix Facilitates Accurate Detection of Atrial Fibrillation in Stroke Patients, June 2019, Stroke

• Electrocardiomatrix: A new method for beat-by-beat visualization and inspection of cardiac signals, 2015, Journal of Integrative Cardiology

Microsurgery

• Simplifying Arterial Coupling in Microsurgery-A Preclinical Assessment of an Everter Device to Aid with Arterial Anastomosis

Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients

• Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients, March 2013, Artificial Intelligence in Medicine

Severe Cardiac Event Prediction System

• Prediction of cardiac arrhythmia using deterministic probabilistic finite-state automata, January 2021, Biomedical Signal Processing and Control

• Markov Models for Detection of Ventricular Arrhythmia, October 2019, IEEE

• Supraventricular Tachycardia Detection via Machine Learning Algorithms, January 2019, IEEE

• A Novel Atrial Fibrillation Prediction Algorithm Applicable to Recordings from Portable Devices, Oct 2018, IEEE

Weil publications relating to our research and products in the area of Trauma and Combat Casualty Care.

Blood Biomarker Guided Diagnosis System for Inflammation

• An Integrated Plasmo-Photoelectronic Nanostructure Biosensor Detects an Infection Biomarker Accompanying Cell Death in Neutrophils, Dec 3, 2019, Small Journal

• Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays, March 20, 2015, ACS Publications

• AC Electroosmosis-Enhanced Nanoplasmofluidic Detection of Ultralow-Concentration Cytokine, March 15, 2017, ACS Publications

• Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure, June 22, 2016, ACS Pub

• Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, MARCH 25, 2021, Blood

• Biotunable Nanoplasmonic Filter on Few-Layer MoS2 for Rapid and Highly Sensitive Cytokine Optoelectronic Immunosensing, May 10, 2017, ACS Pub

DRIVE

• Dynamic Limb Bioimpedance and Inferior Vena Cava Ultrasound in Patients Undergoing Hemodialysis, August 2016, ASAIO

• Continuous Inferior Vena Cava Diameter Tracking through an Iterative Kanade–Lucas–Tomasi-Based Algorithm,Sept 10, 2018, Ultrasound in Medicine & Biology

GROA

• A review of two emerging technologies for pre-hospital treatment of non-compressible abdominal hemorrhage, June 2022, Transfusion

• Tandem use of Gastroesophageal Resuscitative Occlusion of the Aorta followed by REBOA in a Lethal Liver Laceration Model, June 2022, Journal of Trauma & Acute Care Surgery

• Gastroesophageal resuscitative occlusion of the aorta prolongs survival in a lethal liver laceration model, May 2022, Journal of Trauma & Acute Care Surgery

• Gastroesophageal resuscitative occlusion of the aorta: Physiologic tolerance in a swinemodel of hemorrhagic shock, December 2020, Trauma & Acute Care Surgery

Intra-Peritoneal Hemostasis Device (IPHD)

• A review of two emerging technologies for pre-hospital treatment of non-compressible abdominal hemorrhage, June 2022, Transfusion

• Novel intraperitoneal hemostasis device prolongs survival in a swine model of noncompressible abdominal hemorrhage, May 2021, Journal of Trauma and Acute Care Surgery

Microvascular Tissue Oximetry

• Resonance Raman Spectroscopy Derived Tissue Hemoglobin Oxygen Saturation in Critically Ill and Injured Patients, November 17, 2020, Shock

Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients

• Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients, March 2013, Artificial Intelligence in Medicine

Optic Nerve Sheath Diameter

• Automated Optic Nerve Sheath Diameter Measurement Using Super-pixel Analysis

TOBI

• Trans-ocular brain impedance index for assessment of cerebral autoregulation in a porcine model of cerebral hemodynamic perturbation, July 14, 2020, Journal of Clinical Monitoring and Computing

• Novel Noninvasive Method of Cerebrovascular Blood Volume Assessment Using Brain Bioimpedance, November 15, 2017, Journal of Neurotrauma

VATMOS

• Tracking Peripheral Artery Motion and Vascular Resistance With a Multimodal Wearable Sensor Under Pressure Perturbations, August 2022, Journal of Biomechanical Engineering

• Detection of Low Cardiac Index using a Polyvinylidene Fluoride-Based Wearable Ring and Convolutional Neural Networks, IEEE Sensors Journal, doi: 10.1109/JSEN.2020.3022273.

• Decompensation Prediction in Hemodialysis by a Feedback Model as Identified by Miniature Wearable Sensors, 2019 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM), 2019, pp. 133-138, doi: 10.1109/AIM.2019.8868558.

• Identification of Compensatory Arterial Dynamics in Swine Using a Non-Invasive Sensor for Local Vascular Resistance. Proceedings of the ASME 2018 Dynamic Systems and Control Conference. Volume 1: Advances in Control Design Methods; Advances in Nonlinear C

• Abstract 16415: Stratification of Cardiac Index Using a Novel Non-Invasive Ring and Deep Learning, Circulation. Nov. 2018;138:A16415

• Non-invasive vascular resistance monitoring with a piezoelectric sensor and photoplethysmogram, Sensors and Actuators ,Volume 263, 15 August 2017, Pages 198-208

• Estimation of peripheral artery radius using non-invasive sensors and Kalman filtering of local dynamics, 2017 American Control Conference (ACC), 2017, pp. 807-812, doi: 10.23919/ACC.2017.7963052.

• An extended Kalman filter with inequality constraints for real-time detection of intradialytic hypotension, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017, pp. 2227-2230, doi: 10.1109/EMBC.20

• Abstract 19409: Noninvasive Peripheral Vascular Resistance Measured by a Polyvinylidene Fluoride Sensor Identifies Patterns of Oxygen Debt Repayment During Resuscitation After Hemorrhage, Circulation, Vol 134, Nov. 11, 2016

• Real-time detection of intradialytic hypotension using a novel polyvinylidene fluoride based sensor, 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), 2016, pp. 493-496, doi: 10.1109/BHI.2016.7455942.

• Abstract 18257: A Novel Portable Polyvinylidene Fluoride Based Sensor for Detection of Hemorrhage, Circulation, Vol 132, Nov. 10, 2015

Weil publications relating to our research and products in the area of Critical Care Life Support. 

Aerosolve Helmet

• Rapid development of a novel portable negative pressure device, July 1, 2020, International Union Against Tuberculosis and Lung Disease

Aerosolve Tent 

• Rapid development of a portable negative pressure procedural tent, July 1, 2020, International Union Against Tuberculosis and Lung Disease

Bedside Assay Analysis System with Real-time Results

• Machine learning-based cytokine microarray digital immunoassay analysis, May 2021, Biosensors & Bioelectronics

• A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring, Nov. 2020, Lab on a Chip

• Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, March 25, 2021, Blood

Blood Biomarker Guided Diagnosis System for Inflammation

• An Integrated Plasmo-Photoelectronic Nanostructure Biosensor Detects an Infection Biomarker Accompanying Cell Death in Neutrophils, Dec 3, 2019, Small Journal

• Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays, March 20, 2015, ACS Publications

• AC Electroosmosis-Enhanced Nanoplasmofluidic Detection of Ultralow-Concentration Cytokine, March 15, 2017, ACS Publications

• Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure, June 22, 2016, ACS Pub

• Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, MARCH 25, 2021, Blood

• Biotunable Nanoplasmonic Filter on Few-Layer MoS2 for Rapid and Highly Sensitive Cytokine Optoelectronic Immunosensing, May 10, 2017, ACS Pub

DRIVE

• Dynamic Limb Bioimpedance and Inferior Vena Cava Ultrasound in Patients Undergoing Hemodialysis, August 2016, ASAIO

• Continuous Inferior Vena Cava Diameter Tracking through an Iterative Kanade–Lucas–Tomasi-Based Algorithm,Sept 10, 2018, Ultrasound in Medicine & Biology

Intra-Peritoneal Hemostasis Device (IPHD)

• Novel intraperitoneal hemostasis device prolongs survival in a swine model of noncompressible abdominal hemorrhage, May 2021, Journal of Trauma and Acute Care Surgery

Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients

• Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients, March 2013, Artificial Intelligence in Medicine

PICTURE

• Validation and comparison of PICTURE analytic and Epic Deterioration Index for COVID-19, July 10, 2020, MedRxIV

• Demonstrating the consequences of learning missingness patterns in early warning systems for preventative health care: A novel simulation and solution, October 20202, Journal of Biomedical Informatics

• Predicting Intensive Care Transfers and Other Unforeseen Events: Analytic Model Validation Study and Comparison to Existing MethodsRedox Point-of-Care Platform, JMIR Medical Informatics, April 2021

• Electrochemical properties of nanostructured porous gold electrodes in biofouling solutions, 2013 Dec 3;85(23):11610-8. doi: 10.1021/ac403013r. Epub 2013 Nov 18, Analytical Chemistry

• Whole Blood Redox Potential Correlates With Progressive Accumulation of Oxygen Debt and Acts as A Marker of Resuscitation in A Swine Hemorrhagic Shock Model, March 2018, Shock

Therapeutic Vibration Device

• Effect of Multi-Frequency Whole-Body Vibration on Muscle Activation, Metabolic Cost and Regional Tissue Oxygenation, August 12, 2020, IEEE

VATMOS

• Tracking Peripheral Artery Motion and Vascular Resistance With a Multimodal Wearable Sensor Under Pressure Perturbations, August 2022, Journal of Biomechanical Engineering

• Detection of Low Cardiac Index using a Polyvinylidene Fluoride-Based Wearable Ring and Convolutional Neural Networks, IEEE Sensors Journal, doi: 10.1109/JSEN.2020.3022273.

• Decompensation Prediction in Hemodialysis by a Feedback Model as Identified by Miniature Wearable Sensors, 2019 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM), 2019, pp. 133-138, doi: 10.1109/AIM.2019.8868558.

• Identification of Compensatory Arterial Dynamics in Swine Using a Non-Invasive Sensor for Local Vascular Resistance. Proceedings of the ASME 2018 Dynamic Systems and Control Conference. Volume 1: Advances in Control Design Methods; Advances in Nonlinear C

• Abstract 16415: Stratification of Cardiac Index Using a Novel Non-Invasive Ring and Deep Learning, Circulation. Nov. 2018;138:A16415

• Non-invasive vascular resistance monitoring with a piezoelectric sensor and photoplethysmogram, Sensors and Actuators ,Volume 263, 15 August 2017, Pages 198-208

• Estimation of peripheral artery radius using non-invasive sensors and Kalman filtering of local dynamics, 2017 American Control Conference (ACC), 2017, pp. 807-812, doi: 10.23919/ACC.2017.7963052.

• An extended Kalman filter with inequality constraints for real-time detection of intradialytic hypotension, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017, pp. 2227-2230, doi: 10.1109/EMBC.20

• Abstract 19409: Noninvasive Peripheral Vascular Resistance Measured by a Polyvinylidene Fluoride Sensor Identifies Patterns of Oxygen Debt Repayment During Resuscitation After Hemorrhage, Circulation, Vol 134, Nov. 11, 2016

• Real-time detection of intradialytic hypotension using a novel polyvinylidene fluoride based sensor, 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), 2016, pp. 493-496, doi: 10.1109/BHI.2016.7455942.

• Abstract 18257: A Novel Portable Polyvinylidene Fluoride Based Sensor for Detection of Hemorrhage, Circulation, Vol 132, Nov. 10, 2015

Collection of all Weil publications relating to our products and core research focus areas. 

Aerosolve Helmet

• Rapid development of a novel portable negative pressure device, July 1, 2020, International Union Against Tuberculosis and Lung Disease

Aerosolve Tent 

• Rapid development of a portable negative pressure procedural tent, July 1, 2020, International Union Against Tuberculosis and Lung Disease

AHI

• A Signal Processing Approach for Detection of Hemodynamic Instability before Decompensation, February 12, 2016, PLOS

Analytic for Predicting ARDS

• Learning Using Partially Available Privileged Information and Label Uncertainty: Application in Detection of Acute Respiratory Distress Syndrome, July 10, 2020, IEEE Journal of Biomedical and Health Informatics

• Robust segmentation of lung in chest x-ray: applications in analysis of acute respiratory distress syndrome, October 15, 2020, BMC of Medical Imaging

• Signal quality measure for pulsatile physiological signals using morphological features: Applications in reliability measure for pulse oximetry, 2019, Informatics in Medicine Unlocked

ARDS Model

• A novel swine model of the acute respiratory distress syndrome using clinically relevant injury exposures

Automated Brain Image Analysis of Subdural Hematoma

• Novel Algorithm for Automated Optic Nerve Sheath Diameter Measurement Using a Clustering Approach Military Medicine, Volume 186, Issue Supplement_1, January-February 2021, Pages 496–501,

• Automated Segmentation and Severity Analysis of Subdural Hematoma for Patients with Traumatic Brain Injuries, Diagnostics 2020, 10(10), 773

• Automated hematoma segmentation and outcome prediction for patients with traumatic brain injury, Artificial Intelligence in Medicine, Vol 107, July 2020

• Midline Shift vs. Mid-Surface Shift: Correlation with Outcome of Traumatic Brain Injuries, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

• Automated Optic Nerve Sheath Diameter Measurement Using Super-pixel Analysis, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, pp 2793-2796, doi: 10.1109/EMBC.2019.8856449

• Brain Hematoma Segmentation Using Active Learning and an Active Contour Model. In: Rojas I., Valenzuela O., Rojas F., Ortuño F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2019. Lecture Notes in Computer Science, vol 11466. Springer, Cham.

• Hematoma Segmentation Using Dilated Convolutional Neural Network, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018, pp. 5902-5905

• Automatic Midline Shift Detection in Traumatic Brain Injury, 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2018

Bacterial Translocation in Sepsis: A Multifaceted Molecular Approach

• Bacterial Dissemination to the Brain in Sepsis, March 15, 2018, American Journal of Respiratory and Critical Care Medicine Volume 197 Number 6

• Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome, July 18, 2016, Nature Microbiology

• Bacterial Dissemination to the Brain in a Murine Model of Treated Sepsis, 2016, American Journal of Respiratory and Critical Care Medicine

Bedside Assay Analysis System with Real-time Results

• Machine learning-based cytokine microarray digital immunoassay analysis, May 2021, Biosensors & Bioelectronics

• A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring, Nov. 2020, Lab on a Chip

• Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, March 25, 2021, Blood

Blood Biomarker Guided Diagnosis System for Inflammation

• An Integrated Plasmo-Photoelectronic Nanostructure Biosensor Detects an Infection Biomarker Accompanying Cell Death in Neutrophils, Dec 3, 2019, Small Journal

• Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays, March 20, 2015, ACS Publications

• AC Electroosmosis-Enhanced Nanoplasmofluidic Detection of Ultralow-Concentration Cytokine, March 15, 2017, ACS Publications

• Multiplexed Nanoplasmonic Temporal Profiling of T-Cell Response under Immunomodulatory Agent Exposure, June 22, 2016, ACS Pub

• Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders, MARCH 25, 2021, Blood

• Biotunable Nanoplasmonic Filter on Few-Layer MoS2 for Rapid and Highly Sensitive Cytokine Optoelectronic Immunosensing, May 10, 2017, ACS Pub

Breath Analysis Device for Lung Disease Detection

• Rapid breath analysis for acute respiratory distress syndrome diagnostics using a portable two-dimensional gas chromatography device, August, 2019, Analytic & Bioanalytic Chemistry

Cardiac Arrest

• Intrastate Variation in Treatment and Outcomes of Out-of-Hospital Cardiac Arrest

• Aerosol generation during chest compression and defibrillation in a swine cardiac arrest model

• Dose optimization of early high-dose valproic acid for neuroprotection in a swine cardiac arrest model

Detect ARDS

• Deep learning to detect acute respiratory distress syndrome on chest radiographs: a retrospective study with external validation, April 20, 2021, Lancet

Diagnostic Tool for Coagulation Abnormalities in TBI

• A droplet-based microfluidic viscometer for the measurement of blood coagulation, Jan 2020, Biomicrofluidics

DRIVE

• Dynamic Limb Bioimpedance and Inferior Vena Cava Ultrasound in Patients Undergoing Hemodialysis, August 2016, ASAIO

• Continuous Inferior Vena Cava Diameter Tracking through an Iterative Kanade–Lucas–Tomasi-Based Algorithm,Sept 10, 2018, Ultrasound in Medicine & Biology

Electrocardiomatrix (ECM)

• Accurate detection of atrial fibrillation and atrial flutter using the electrocardiomatrix technique, August 2018, J Electrocardiology

• Electrocardiomatrix facilitates qualitative identification of diminished heart rate variability in critically ill patients shortly before cardiac arrest, August 2018, J Electrocardiology

• Electrocardiomatrix Facilitates Accurate Detection of Atrial Fibrillation in Stroke Patients, June 2019, Stroke

• Electrocardiomatrix: A new method for beat-by-beat visualization and inspection of cardiac signals, 2015, Journal of Integrative Cardiology

GROA

• A review of two emerging technologies for pre-hospital treatment of non-compressible abdominal hemorrhage, June 2022, Transfusion

• Tandem use of Gastroesophageal Resuscitative Occlusion of the Aorta followed by REBOA in a Lethal Liver Laceration Model, June 2022, Journal of Trauma & Acute Care Surgery

• Gastroesophageal resuscitative occlusion of the aorta prolongs survival in a lethal liver laceration model, May 2022, Journal of Trauma & Acute Care Surgery

• Gastroesophageal resuscitative occlusion of the aorta: Physiologic tolerance in a swine model of hemorrhagic shock, December 2020, Trauma & Acute Care Surgery

Intra-Peritoneal Hemostasis Device (IPHD)

• A review of two emerging technologies for pre-hospital treatment of non-compressible abdominal hemorrhage, June 2022, Transfusion

• Novel intraperitoneal hemostasis device prolongs survival in a swine model of noncompressible abdominal hemorrhage, May 2021, Journal of Trauma and Acute Care Surgery

Microsurgery

• Simplifying Arterial Coupling in Microsurgery-A Preclinical Assessment of an Everter Device to Aid with Arterial Anastomosis

Microvascular Tissue Oximetry

• Resonance Raman Spectroscopy Derived Tissue Hemoglobin Oxygen Saturation in Critically Ill and Injured Patients, November 17, 2020, Shock

Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients

• Multimodal Platform for Continuous Monitoring and Decision Support for Postoperative Cardiac Patients, March 2013, Artificial Intelligence in Medicine

Optic Nerve Sheath Diameter

• Automated Optic Nerve Sheath Diameter Measurement Using Super-pixel Analysis

PICTURE

• Validation and comparison of PICTURE analytic and Epic Deterioration Index for COVID-19, July 10, 2020, MedRxIV

• Demonstrating the consequences of learning missingness patterns in early warning systems for preventative health care: A novel simulation and solution, October 20202, Journal of Biomedical Informatics

PICTURE-Sepsis

• Demonstrating the consequences of learning missingness patterns in early warning systems for preventative health care: A novel simulation and solution. J Biomed Inform. 2020 Oct;110:103528

Point-of-Care Microfluidic Platform for Detecting Traumatic Brain Injury

• Variable-height channels for microparticle characterization and display, 21 July 2020, Issue 14, Lab on a Chip,

Rapid Diagnostic for Personalized Treatment in Sepsis and Other Infections

• Shell-Engineered Chiroplasmonic Assemblies of Nanoparticles for Zeptomolar DNA Detection, Nano Lett. 2014, 14, 7, 3908–3913
  Publication Date:May 23, 2014

• Attomolar DNA detection with chiral nanorod assemblies. Nat Commun4, 2689 (2013)

• Reducing exposure to broad-spectrum antibiotics for bloodstream infection, JLPM, Vol 3 December 2018

Rapid Pathogen Identification in Pneumonia Using Real-time Metagenomics and Ultra-sensitive PCR

• Rapid Pathogen Identification in Bacterial Pneumonia Using Real-Time Metagenomics, May 5, 2017, American Journal of Respiratory and Critical Care Medicine

Redox Point-of-Care Platform

• Electrochemical properties of nanostructured porous gold electrodes in biofouling solutions, 2013 Dec 3;85(23):11610-8. doi: 10.1021/ac403013r. Epub 2013 Nov 18, Analytical Chemistry

• Whole Blood Redox Potential Correlates With Progressive Accumulation of Oxygen Debt and Acts as A Marker of Resuscitation in A Swine Hemorrhagic Shock Model, March 2018, Shock

Sepsis Model

• A comprehensive assessment of multi-system responses to a renal inoculation of uropathogenic E. coli in swine

Severe Cardiac Event Prediction System

• Prediction of cardiac arrhythmia using deterministic probabilistic finite-state automata, January 2021, Biomedical Signal Processing and Control

• Markov Models for Detection of Ventricular Arrhythmia, October 2019, IEEE

• Supraventricular Tachycardia Detection via Machine Learning Algorithms, January 2019, IEEE

• A Novel Atrial Fibrillation Prediction Algorithm Applicable to Recordings from Portable Devices, Oct 2018, IEEE

The Role of the Lung Microbiome in Oxygen-Induced Lung Injury

• The role of the bacterial microbiome in lung disease, Published online: 09 Jan 2014, Expert Review of Respiratory Medicine

• The Microbiome and the Respiratory Tract, Februay 2016, Annual Review of Physiology

• Understanding the role of the microbiome in chronic obstructive pulmonary disease: principles, challenges, and future directions, January 1, 2017, Translational Research

• The bacterial microbiota in inflammatory lung diseases, August 2015, Clinical Immunology

Therapeutic Vibration Device

• Effect of Multi-Frequency Whole-Body Vibration on Muscle Activation, Metabolic Cost and Regional Tissue Oxygenation, August 12, 2020, IEEE

TOBI

• Trans-Ocular Brain Impedance Indices Predict Pressure Reactivity Index Changes in a Porcine Model of Hypotension and Cerebral Autoregulation Perturbation, February 2022, Neurocritical Care

• Trans-ocular brain impedance index for assessment of cerebral autoregulation in a porcine model of cerebral hemodynamic perturbation, July 14, 2020, Journal of Clinical Monitoring and Computing

• Novel Noninvasive Method of Cerebrovascular Blood Volume Assessment Using Brain Bioimpedance, November 15, 2017, Journal of Neurotrauma

VATMOS

• Tracking Peripheral Artery Motion and Vascular Resistance With a Multimodal Wearable Sensor Under Pressure Perturbations, August 2022, Journal of Biomechanical Engineering

• Detection of Low Cardiac Index using a Polyvinylidene Fluoride-Based Wearable Ring and Convolutional Neural Networks, IEEE Sensors Journal, doi: 10.1109/JSEN.2020.3022273.

• Decompensation Prediction in Hemodialysis by a Feedback Model as Identified by Miniature Wearable Sensors, 2019 IEEE/ASME International Conference on Advanced Intelligent Mechatronics (AIM), 2019, pp. 133-138, doi: 10.1109/AIM.2019.8868558.

• Identification of Compensatory Arterial Dynamics in Swine Using a Non-Invasive Sensor for Local Vascular Resistance. Proceedings of the ASME 2018 Dynamic Systems and Control Conference. Volume 1: Advances in Control Design Methods; Advances in Nonlinear C

• Abstract 16415: Stratification of Cardiac Index Using a Novel Non-Invasive Ring and Deep Learning, Circulation. Nov. 2018;138:A16415

• Non-invasive vascular resistance monitoring with a piezoelectric sensor and photoplethysmogram, Sensors and Actuators ,Volume 263, 15 August 2017, Pages 198-208

• Estimation of peripheral artery radius using non-invasive sensors and Kalman filtering of local dynamics, 2017 American Control Conference (ACC), 2017, pp. 807-812, doi: 10.23919/ACC.2017.7963052.

• An extended Kalman filter with inequality constraints for real-time detection of intradialytic hypotension, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2017, pp. 2227-2230, doi: 10.1109/EMBC.20

• Abstract 19409: Noninvasive Peripheral Vascular Resistance Measured by a Polyvinylidene Fluoride Sensor Identifies Patterns of Oxygen Debt Repayment During Resuscitation After Hemorrhage, Circulation, Vol 134, Nov. 11, 2016

• Real-time detection of intradialytic hypotension using a novel polyvinylidene fluoride based sensor, 2016 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), 2016, pp. 493-496, doi: 10.1109/BHI.2016.7455942.

• Abstract 18257: A Novel Portable Polyvinylidene Fluoride Based Sensor for Detection of Hemorrhage, Circulation, Vol 132, Nov. 10, 2015