![als](https://research-dev.uofmhealth.org/sites/default/files/styles/jumbo_16_9/public/2024-02/nerurology-research.jpeg?h=3a025696&itok=Oq1NgNPK)
A world leader in the fight against amyotrophic lateral sclerosis (ALS), the ALS Center of Excellence at Michigan Medicine features a combination of renowned researchers, unrivaled facilities, and the partnership of a dedicated multidisciplinary clinic team.
We are collaborating with research leaders worldwide on a multifaceted approach to understanding the causes of ALS, developing more effective treatments, and one day making ALS a preventable disease.
Amyotrophic lateral sclerosis (ALS) is often referred to as Lou Gehrig’s disease. Motor neurons in the brain and spinal cord degenerate, leading to loss of muscle function and eventually death.
![Scott Matzka dropping the puck at the IceALS game](https://research-dev.uofmhealth.org/sites/default/files/styles/jumbo_16_9/public/2024-04/matzka-calderone-iceals.jpg?h=8e9dfc49&itok=bXVU0bot)
![clinical_studies](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-04/clinical_studies-neuronetworksep23_298.jpg?h=b69e0e0e&itok=v_FhzOer)
![als](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-02/alsss.jpg?h=c3d172f9&itok=g162sQOW)
The Pranger ALS Clinic is the site for clinical and observational research for the ALS Center of Excellence. It is committed to providing compassionate care to patients with ALS. Fighting ALS requires a large, dedicated multidisciplinary team, such as the exceptional group we have assembled at the University of Michigan.
![an AI generated image of neutrofils and nerves](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-05/neutrofils_and_nerves_596588151.jpeg?h=d4d90d85&itok=-Up8HmUZ)
![a photo of a dancer](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-05/als_dance_event_square_image_with_red.jpg?h=e1a11df2&itok=cFOCDsv2)
![An MRI (parasagittal FLAIR) demonstrates increased T2 signal within the posterior part of the internal capsule and can be tracked to the subcortical white matter of the motor cortex, outlining the corticospinal tract), consistent with the clinical diagnosis of ALS](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-05/wcmu.png?h=55de6620&itok=S0jfs97L)
![graphic for ALS Awareness Month](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-05/als_awareness_787135249_16x9.jpg?h=437d2615&itok=Bs7f8jQX)
![crop of Go On, Be Brave flier](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-05/flyer_for_gobb.png?h=986eee9e&itok=AKSc5Zw0)
![a photo of Dr. Eva Feldman receiving the Sheila Essey Award with James Essey](https://research-dev.uofmhealth.org/sites/default/files/styles/card/public/2024-04/sheila_essey_2024_photo_courtesy_of_the_american_academy_of_neurology_-_dr._eva_feldman_-_sheila_essey_award_-_photo_1.png?h=0f77222d&itok=rJDf0k7C)