LUCID

LUCID is a non-invasive therapeutic device that uses unique wavelengths of infrared light (IRL) to directly modulate mitochondrial activity and prevent generation of free radicals to improve cell survival and neurological outcomes.

Value Proposition

IRL technology has a variety of clinical advantages, including the potential to treat multiple types of TBI non-invasively. Mitochondrial dysfunction has been found to be a significant factor in the progression of secondary brain injury. LUCID efficiently and safely delivers deeply penetrating infrared light (IRL) of a specific wavelength combination shown to effectively prevent the formation of toxic free radicals in the brain following TBI.

Competitive Advantage

The infrared light treatment device will efficiently and safely deliver deeply penetrating infrared light (IRL) of a specific wavelength combination shown to effectively prevent the formation of toxic free radicals in the brain following TBI.

The delivery interface is capable of non-invasively delivering therapeutic light into the human brain and is easy to deploy at the bedside and/or in the field.

Unique Features

  • Completely Non-Invasive

  • Easy to Deploy at the Bedside and in the Field

  • Delivers Therapeutic Light Deeply into Brain

  • Safe and Efficient

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Licensing Information
Mitovation in 2018

Principal Investigators
Tom Sanderson, PhD
Joe Wider, PhD

Intellectual Property
Invention Disclosure # 2019-293, 2021-403

Solution Sheet
Download Solution Sheet (PDF)

MARKET OPPORTUNITY

Together with existing feasibility, safety and efficacy studies, IRL can provide a robust and safe treatment option for any head trauma, irrespective of the heterogeneous nature of TBI. In addition to the >5,500 hospitals in the US, this device can be used in non-hospital facilities, such as schools, athletic buildings and in combat territories.

By applying a novel therapeutic technology, infrared light (IRL) irradiation, this device can target the cellular injury processes following head trauma. Based on the molecular events that contribute to the secondary injury of TBI, IRL will reduce cell death and improve recovery by treating the early stages (up to 4 hours) following TBI.

Contact Mitovation for more information about investment and partnership opportunities.

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Image courtesy of project team

  • $491,211 in non-dilutive funding

  • 2018 $99,686 Massey Grand Challenge

  • 2019 $182,841 Massey Grand Challenge

  • 2019 $40,000 Schwabauer Accelerator Award

  • 2020 $170,939 NIH

  • 2020 $135,109 Massey Grand Challenge

  • 2021 $168,948 Massey Grand Challenge

  • 2021 $40,000 Schwabauer Accelerator Award

  • 2022 $154,219 Massey Grand Challenge

  • Substantial additional departmental, school and center based support

 

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