Cindy H Hsu, MD, PhD, MS
Division Chief of Critical Care
Associate Professor of Emergency Medicine
Associate Professor of Surgery
Emergency Medicine
1500 E. Medical Center Dr.
Ann Arbor, MI 48109-5303
[email protected]

Available to mentor
Cindy H Hsu, MD, PhD, MS
Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • About

    Dr. Cindy Hsu is an emergency medicine physician and surgical intensivist who cares for patients in Michigan Medicine’s Adult Emergency Department, Emergency Critical Care Center, and Trauma/Burn Intensive Care Unit. Dr. Hsu received her undergraduate degree from the Johns Hopkins University and MD/PhD degree from Boston University School of Medicine with a doctoral degree in Pharmacology & Experimental Therapeutics and Biomedical Neuroscience. She then completed her emergency medicine residency at the Hospital of the University of Pennsylvania followed by trauma/surgical critical care fellowship at the R Adams Cowley Shock Trauma Center. Wanting to bridge the translational gap between bench and bedside, she completed a master’s degree in Clinical Trial Design & Statistical Analysis at the University of Michigan School of Public Health. Dr. Hsu is among the first in her specialty to hold dual certifications in emergency medicine and surgical critical care. As such, she is uniquely poised to impact the care of critical ill patients from the moment they arrive in the emergency department through their stay in the intensive care units.

    Dr. Hsu is the current Chief of the Division of Critical Care in the UM Department of Emergency Medicine. Dr. Hsu strives to transform cardiac arrest care by dismantling the gaps between translational research and clinical implementation, with an emphasis on improving the neurologic outcome of cardiac arrest patients. Her research has spanned from large animal models to clinical trials of out-of-hospital cardiac arrest and other acute conditions, to mixed methods research on emergency trial conducts. Dr. Hsu has dedicated significant time as an NHLBI K12 Scholar developing large animal cardiac arrest models to study neuroprotective therapies after cardiac arrest such as high-dose valproic acid, with plan to translate these findings to early phase clinical trials. The significance of her work was recognized by a NINDS R61/33 Innovation Grant to Nurture Initial Translational Efforts(link is external), which will enable her team to overcome the translational barrier of existing long-term models by developing a clinically relevant and cost-effective short-term cardiac arrest swine model of severe brain injury. Dr. Hsu also serves as a co-investigator for the Strategies to Innovate Emergency Care Clinical Trials Network (SIREN)(link is external) Clinical Coordinating Center as well as the site principal investigator for several multicenter cardiac arrest clinical trials such as ICECAP(link is external). She has been actively involved in the creation of resuscitation guidelines as a member on the International Liaison Committee on Resuscitation’s Advanced Life Support Task Force and the American Heart Association’s Emergency Cardiovascular Care Science Subcommittee. Her accomplishments in cardiac arrest research has been recognized by several national awards including the 2019 Society of Academic Emergency Medicine Academy for Women in Academic Emergency Medicine Early Career Award, 2020 AHA Resuscitation Science Symposium Young Investigator Award, and 2022 Society for Academic Emergency Medicine Early Investigator Award.

    Administrative Contact
    Cindy Trafford
    [email protected]

    Links
    • Faculty Profile
    Qualifications
    • Trauma/Surgical Critical Care Fellow
      R Adams Cowley Shock Trauma Center, Surgery, 2016
    • Resident Physician
      Hospital of the University of Pennsylvania, Emergency Medicine, 2014
    • Chief Resident
      Hospital of the University of Pennsylvania, Emergency Medicine, 2014
    • MS
      University of Michigan, Ann Arbor, 2021
    • MD, PhD
      Boston University School of Medicine, 72 E Concord St, 2010
    • BA
      Johns Hopkins University, Baltimore, 2002
    Center Memberships
    • Center Member
      Center for Integrative Research in Critical Care
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    Research Overview

    Cardiac Arrest
    Traumatic Brain Injury
    Neuroprotection
    Innovations in Simulation Training
    Emergency Critical Care
    Emergency Clinical Trials

    Recent Publications See All Publications
    • Journal Article
      Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest.
      Meurer WJ, Schmitzberger FF, Yeatts S, Ramakrishnan V, Abella B, Aufderheide T, Barsan W, Benoit J, Berry S, Black J, Bozeman N, Broglio K, Brown J, Brown K, Carlozzi N, Caveney A, Cho S-M, Chung-Esaki H, Clevenger R, Conwit R, Cooper R, Crudo V, Daya M, Harney D, Hsu C, Johnson NJ, Khan I, Khosla S, Kline P, Kratz A, Kudenchuk P, Lewis RJ, Madiyal C, Meyer S, Mosier J, Mouammar M, Neth M, O'Neil B, Paxton J, Perez S, Perman S, Sozener C, Speers M, Spiteri A, Stevenson V, Sunthankar K, Tonna J, Youngquist S, Geocadin R, Silbergleit R, ICECAP trial investigators . Trials, 2024 Jul 23; 25 (1): 502 DOI:10.1186/s13063-024-08280-w
      PMID: 39044295
    • Journal Article
      Heads UP CPR: An over elevated promise.
      Gottula AL, Bartos JA, Hsu CH. Resuscitation, 2024 Oct 21; 204: 110418 DOI:10.1016/j.resuscitation.2024.110418
      PMID: 39442790
    • Journal Article
      134: Rethinking EROCA: An Interinstitutional Collaboration Experience of Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital And Emergency Department Cardiac Arrest.
      Hsu C-Y, Hsu C. ASAIO Journal, 2024 Sep; 70 (Supplement 4): 13 - 13. DOI:10.1097/01.mat.0001069792.48638.bf
    • Journal Article
      Improving Outcomes After Post-Cardiac Arrest Brain Injury: A Scientific Statement From the International Liaison Committee on Resuscitation.
      Perkins GD, Neumar R, Hsu CH, Hirsch KG, Aneman A, Becker LB, Couper K, Callaway CW, Hoedemaekers CWE, Lim SL, Meurer W, Olasveengen T, Sekhon MS, Skrifvars M, Soar J, Tsai M-S, Vengamma B, Nolan JP, International Liaison Committee on Resuscitation . Circulation, 2024 Jun 27; DOI:10.1161/CIR.0000000000001219
      PMID: 38934122
    • Journal Article
      Corrigendum to "2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces" [Resuscitation 195 (2024) 109992].
      Berg KM, Bray JE, Ng K-C, Liley HG, Greif R, Carlson JN, Morley PT, Drennan IR, Smyth M, Scholefield BR, Weiner GM, Cheng A, Djärv T, Abelairas-Gómez C, Acworth J, Andersen LW, Atkins DL, Berry DC, Bhanji F, Bierens J, Bittencourt Couto T, Borra V, Böttiger BW, Bradley RN, Breckwoldt J, Cassan P, Chang W-T, Charlton NP, Phil Chung S, Considine J, Costa-Nobre DT, Couper K, Dainty KN, Dassanayake V, Davis PG, Dawson JA, Fernanda de Almeida M, De Caen AR, Deakin CD, Dicker B, Douma MJ, Eastwood K, El-Naggar W, Fabres JG, Fawke J, Fijacko N, Finn JC, Flores GE, Foglia EE, Folke F, Gilfoyle E, Goolsby CA, Granfeldt A, Guerguerian A-M, Guinsburg R, Hatanaka T, Hirsch KG, Holmberg MJ, Hosono S, Hsieh M-J, Hsu CH, Ikeyama T, Isayama T, Johnson NJ, Kapadia VS, Daripa Kawakami M, Kim H-S, Kleinman ME, Kloeck DA, Ko Y-C, Kudenchuk P, Kule A, Kurosawa H, Lagina AT, Lauridsen KG, Lavonas EJ, Lee HC, Lin Y, Lockey AS, Macneil F, Maconochie IK, John Madar R, Malta Hansen C, Masterson S, Matsuyama T, McKinlay CJD, Meyran D, Monnelly V, Morrison LJ, Nadkarni V, Nakwa FL, Nation KJ, Nehme Z, Nemeth M, Neumar RW, Nicholson T, Nikolaou N, Nishiyama C, Norii T, Nuthall GA, Ohshimo S, Olasveengen TM, Gene Ong Y-K, Orkin AM, Parr MJ, Patocka C, Perkins GD, Perlman JM, Rabi Y, Raitt J, Ramachandran S, Ramaswamy VV, Raymond TT, Reis AG, Reynolds JC, Ristagno G, Rodriguez-Nunez A, Roehr CC, Rüdiger M, Sakamoto T, Sandroni C, Sawyer TL, Schexnayder SM, Schmölzer GM, Schnaubelt S, Semeraro F, Singletary EM, Skrifvars MB, Smith CM, Soar J, Stassen W, Sugiura T, Tijssen JA, Topjian AA, Trevisanuto D, Vaillancourt C, Wyckoff MH, Wyllie JP, Yang C-W, Yeung J, Zelop CM, Zideman DA, Nolan JP, Collaborators . Resuscitation, 2024 Aug; 201: 110262 DOI:10.1016/j.resuscitation.2024.110262
      PMID: 38937213
    • Journal Article
      Improving Outcomes After Post-Cardiac Arrest Brain Injury: A Scientific Statement From the International Liaison Committee on Resuscitation.
      Perkins GD, Neumar R, Hsu CH, Hirsch KG, Aneman A, Becker LB, Couper K, Callaway CW, Hoedemaekers CWE, Lim SL, Meurer W, Olasveengen T, Sekhon MS, Skrifvars M, Soar J, Tsai M-S, Vengamma B, Nolan JP, International Liaison Committee on Resuscitation . Resuscitation, 2024 Aug; 201: 110196 DOI:10.1016/j.resuscitation.2024.110196
      PMID: 38932555
    • Presentation
      Reimagining Critical Care Delivery in Emergency Medicine
      Hsu C. 2024 Jun 24;
    • Presentation
      University of Michigan Emergency Department: Present and Prospects
      Hsu C. 2024 Jun 24;